The function and homeostasis of bone relies on the balanced bone remodeling process, which is a continuously cycle of bone formation mediated by osteoblasts and resorption mediated by osteoclasts throughout life. Osteoclasts are hematopoietic myeloid lineage and derived from bone marrow-derived monocytes (BMDMs). The defective osteoclast differentiation willdisturb the skeletal architecture and...

One Health provides new solutions to the global health challenges and calls for ideas from the global, regional and national levels to achieve effective integration of resources, eventually sustainably promoting the harmonious union of human health, animal health and environmental health. On May 8th, the Workshop of One Health Action Commission was grandly opened at Shanghai Jiao Tong Universit...

         On 22 April 2023, the launch meeting of a major project of the National Natural Science Foundation of China (NSFC) entitled “Theory and Methodology of Intelligent Healthcare Management”, hosted by theDepartment ofManagement Sciencesof the NSFC and co-organized by the China Hospital Development Institute, was held at the Shanghai Science Hall.Professor Fan Xianqun, Academician of the ...

On May 2rd, 2023, the Journal of the American Medical Association (JAMA), one of the world's top academic journals with an impact factor of 157.335, published the results of a multicenter, randomized, double-blind, placebo-controlled clinical study entitled "Prednisone vs Placebo and Live Birth in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization", jointly conducte...

The team led by Professor Honglin Wang published a research article titled "Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis" online in Nature Communications.

Researchers from the laboratory of Leng-Siew Yeap at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine and Fei-Long Meng at the Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences have reported the results of their groundbreaking study to elucidate the mechanisms that promote somatic hypermutation at the antigen-binding sites of ...