On March 28th,2023,the team of Academician Xianqun Fan from the Department of Ophthalmology atShanghaiNinth People's Hospital, Shanghai Jiao Tong University School of Medicine published a research article titled "Nuclear PD-L1 promotes EGR1-mediated angiogenesis and accelerates tumorigenesis" in Cell Discovery. The study reveals a higher proportion of nuclear programmed cell death ligand 1 (PD...

The article DNA Repair Mechanisms That Promote Insertion-Deletion Events During Immunoglobulin Gene Diversificationwas published in Science Immunology by PI Leng-Siew Yeap Lab of Shanghai Jiao Tong University School of Medicine/Shanghai Institute of Immunology on March 24, 2023, reported the results of their work to elucidate the mechanisms that generate rare mutagenic outcomes of antibody dive...

The article STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretionwas published inImmunityby Professor Junling Liu / Yanyan Xu Lab of Shanghai Jiao Tong University School of Medicine on March 20, 2023, systematically revealed the deep mechanism of how platelets respond to bacterial and other microbial infection stimulation and the relea...

Professor Zhang Jian from Shanghai Jiao Tong University School of Medicine has recently received a congratulatory letter and a certificate from the Royal Society of Chemistry on being elected as the fellow of the Royal Society of Chemistry (FRSC) due to his achievements in new target discovery and innovative medicine chemistry.FRSC, founded in 1841, is a chemistry society with the longest histo...

Biomedical imaging plays crucial roles in cancer diagnosis, intraoperativenavigation, and postoperative assessment. Fluorescence imaging has attracted widespread attention due to its low cost, the ability to offer fast feedback, high sensitivity, and low level of hazardous radiation. There has been an increasing use of biomedical imaging in biomedical research.Conventional optical imaging uses ...

On December 29, the world's leading medical journalThe New England Journal of Medicine (NEJM) published online the phase III registration clinical research (NCT05341609) result of comparing nucleoside drug VV116 (JT001) for oral treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the combination drug of Nirmatrelvir–Ritonavir (PAXLOVID). The result, applied to the pr...